Pathology EMQ.

Name: Tina Mistry

Theme: Myeloproliferative Disorders

OPTION LIST

A	Renal disease	I	Anagrelide
B	Thalidomide	J	Acute lymphoblastic leukaemia
C	Myelofibrosis	K	Bone marrow transplanation
D	Acute myeloid leukaemia	L	Polycythaemia Vera
E	Thrombocytopenia	M	Prednisolone
F	Essential thrombocythaemia	N	Hypoxia
G	Chronic lymphocytic leukemia	O	Chronic granulocytic leukaemia
H	Myeloma	P	Aspirin

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. A 65yr old male is found to have an Hb of 19g/dl on a routine blood test, EPO levels were normal. On examination he is found to have splenomegaly and engorgement of the retinal vein. Bone marrow histology showed increased cellularity of erythoid cells. What is the most likely diagnosis?

2. A 30yr old female was found to have platelets>600x10⁹/L on 3 separate occasions. Her CRP and ESR were within the normal range. She suffered a DVT 3 months ago. What is the likely diagnosis?

3. Which drug aids in the reduction of platelet number and can cause palpitations and flushing?

4. A peripheral blood film of a patient with polycythaemia vera shows a leucoerythroblastic picture with tear drop poikilocytes. What is the likely diagnosis?

5. Imatinib can be used in the treatment for which leukaemia?

ANSWERS

1. L

2. F

3. I

4. C

5. O